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<p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Nature of Operations</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">UroGen Pharma Ltd. is an Israeli company incorporated in <em style="font: inherit;"> April 2004 (</em>“UPL”).</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">UroGen Pharma Inc., a wholly owned subsidiary of UPL, was incorporated in Delaware in <em style="font: inherit;"> October 2015 </em>and began operating in <em style="font: inherit;"> February 2016 (</em>“UPI”).</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">UPL and UPI (together the “Company”) is a biotechnology company dedicated to developing and commercializing innovative solutions that treat urothelial and specialty cancers. Since commencing operations, the Company has devoted substantially all of its efforts to securing intellectual property rights, performing research and development activities, including conducting clinical trials and manufacturing activities, hiring personnel, launching the Company’s <em style="font: inherit;">first</em> commercial product, <i>Jelmyto</i> (mitomycin) for pyelocalyceal solution, formerly known as UGN-<em style="font: inherit;">101,</em> clinical development of UGN-<em style="font: inherit;">102,</em> and raising capital to support and expand these activities.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">On <em style="font: inherit;"> April 15, 2020, </em>the U.S. Food and Drug Administration (“FDA”) granted expedited approval for <i>Jelmyto</i>, a <em style="font: inherit;">first</em>-in-class treatment indicated for adults with low-grade upper tract urothelial cancer (“low-grade UTUC”). <i>Jelmyto</i> consists of mitomycin, an established chemotherapy, and sterile hydrogel, using our proprietary sustained release RTGel technology. It has been designed to enable longer exposure of urinary tract tissue to mitomycin, thereby enabling the treatment of tumors by non-surgical means.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">2</em> </b>–<b> Basis of Presentation</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;margin:0pt 0pt 0pt 8pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with U.S. generally accepted accounting principles (“GAAP”) for interim financial information and in accordance with the instructions to Form <em style="font: inherit;">10</em>-Q and Article <em style="font: inherit;">10</em> of Regulation S-<em style="font: inherit;">X.</em> Accordingly, they do <em style="font: inherit;">not</em> include all the information and footnotes required by GAAP for complete financial statements. In the opinion of the Company’s management, the accompanying condensed consolidated financial statements contain all adjustments (consisting of normal recurring accruals and adjustments) necessary for fair statement of its financial position, results of operations and cash flows of the Company at the dates and for the periods indicated. Interim results are <em style="font: inherit;">not</em> necessarily indicative of results for the full fiscal year. The year-end condensed consolidated balance sheet data was derived from audited financial statements but does <em style="font: inherit;">not</em> include all disclosures required by accounting principles generally accepted in the United States. The unaudited condensed consolidated financial statements should be read in conjunction with the consolidated financial statements and the notes thereto contained in the Company’s Annual Report on Form <em style="font: inherit;">10</em>-K for the year ended <em style="font: inherit;"> December </em><em style="font: inherit;">31,</em> <em style="font: inherit;">2021,</em> as filed with the Securities and Exchange Commission (“SEC”) on <em style="font: inherit;"> March 21, 2022.</em></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company has experienced net losses since its inception and has an accumulated deficit o<span style="background-color:#ffffff;">f $495.7</span> million and $467.3 million as of <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;"> December </em><em style="font: inherit;">31,</em> <em style="font: inherit;">2021,</em> respectively. The Company expects to incur losses and have negative net cash flows from operating activities as it executes on its strategy including engaging in further research and development activities, particularly conducting non-clinical studies and clinical trials.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The success of the Company depends on the ability to successfully commercialize its technologies to support its operations and strategic plan. Based on management’s cash flow projections the Company believes that its cash and cash equivalents and marketable securities are sufficient to fund the Company’s planned operations for at least the next <em style="font: inherit;">12</em> months. The Company anticipates that it will need to raise additional capital in the future. There can be <em style="font: inherit;">no</em> assurances that the Company will be able to secure such additional financing if at all, or on terms that are satisfactory to the Company, and that it will be sufficient to meet its needs. In the event the Company is <em style="font: inherit;">not</em> successful in obtaining sufficient funding, this could force us to delay, limit, or reduce our product development, commercialization efforts or other operations.</p> -495700000 -467300000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">3</em> </b>–<b> Significant Accounting Policies</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Principles of Consolidation</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The condensed consolidated financial statements include the accounts of UPL and its subsidiary, UPI. Intercompany balances and transactions have been eliminated during consolidation.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Use of Estimates</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenue and expense during the reporting period. Actual results <em style="font: inherit;"> may </em>differ from those estimates. As applicable to the unaudited condensed consolidated financial statements, the critical accounting estimates relate to the fair value of share-based compensation, measurement of revenue, estimate of uncertain tax positions, and measurement of liabilities accounted for under the interest method.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Functional Currency</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The U.S. dollar (“Dollar”) is the currency of the primary economic environment in which the operations of the Company are conducted. Therefore, the functional currency of the Company is the Dollar.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Accordingly, transactions in currencies other than the Dollar are measured and recorded in the functional currency using the exchange rate in effect at the date of the transaction. At the balance sheet date, monetary assets and liabilities that are denominated in currencies other than the Dollar are measured using the official exchange rate at the balance sheet date. The effects of foreign currency re-measurements are recorded in the condensed consolidated statements of operations as “Interest and other income, net.”</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Cash and Cash Equivalents; Marketable Securities</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company considers all highly liquid investments with an original maturity of <em style="font: inherit;">three</em> months or less when purchased to be cash equivalents. Cash and cash equivalents consist primarily of money market funds and bank money market accounts and are stated at cost, which approximates fair value. Restricted cash is related primarily to cash held to secure corporate credit cards; restricted deposits are related to cash held to secure leases.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Cash and cash equivalents and marketable securities totaled $137.1 million as of <em style="font: inherit;"> March 31, 2022</em>. The Company classifies its marketable securities as available-for-sale in accordance with the Financial Accounting Standards Board (“FASB”) Accounting Standards Codification (“ASC”) Topic <em style="font: inherit;">320,</em> “Investments — Debt and Equity Securities”. Available-for-sale debt securities are carried at fair value with unrealized gains and losses reported in other comprehensive income/loss within shareholders’ equity. Realized gains and losses are recorded as a component of interest and other income (expense), net. The cost of securities sold is based on the specific-identification method.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Short-term investments are valued using models or other valuation methodologies that use Level <em style="font: inherit;">2</em> inputs. These models are primarily industry-standard models that consider various assumptions, including time value, yield curve, volatility factors, default rates, current market and contractual prices for the underlying financial instruments, as well as other relevant economic measures. The majority of these assumptions are observable in the marketplace, can be derived from observable data or are supported by observable levels at which transactions are executed in the marketplace. </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">For individual debt securities classified as available-for-sale securities where there has been a decline in fair value below amortized cost, the Company determines whether the decline resulted from a credit loss or other factors. The Company records impairment relating to credit losses through an allowance for credit losses, limited by the amount that the fair value is less than the amortized cost basis. Impairment that has <em style="font: inherit;">not</em> been recorded through an allowance for credit losses is recorded through other comprehensive income, net of applicable taxes.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Concentration of Credit Risk</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Financial instruments, which potentially subject the Company to significant concentrations of credit risk, consist primarily of cash and cash equivalents and marketable securities. The primary objectives for the Company’s investment portfolio are the preservation of capital and the maintenance of liquidity. The Company does <em style="font: inherit;">not</em> enter into any investment transaction for trading or speculative purposes.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company’s investment policy limits investments to certain types of instruments such as certificates of deposit, money market instruments, obligations issued by the U.S. government and U.S. government agencies as well as corporate debt securities, and places restrictions on maturities and concentration by type and issuer. The Company maintains cash balances in excess of amounts insured by the Federal Deposit Insurance Corporation and concentrated within a limited number of financial institutions. The accounts are monitored by management to mitigate the risk.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company’s product sales are recognized through the Company's arrangement with a single customer, a <em style="font: inherit;">third</em>-party national specialty distributor. The Company assesses the need for an allowance for doubtful accounts primarily based on creditworthiness, historical payment experience and general economic conditions. The Company has <em style="font: inherit;">not</em> experienced any credit losses related to this customer and has <em style="font: inherit;">not</em> currently recognized any allowance for doubtful accounts.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: justify; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: justify; margin: 0pt;"><b><i>Income Taxes</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company provides for income taxes based on pretax income, if any, and applicable tax rates available in the various jurisdictions in which it operates, including Israel and the U.S. deferred taxes are computed using the asset and liability method. Under the asset and liability method, deferred income tax assets and liabilities are determined based on the differences between the financial reporting and tax bases of assets and liabilities and are measured using the currently enacted tax rates and laws. A valuation allowance is recognized to the extent that it is more likely than <em style="font: inherit;">not</em> that the deferred taxes will <em style="font: inherit;">not</em> be realized in the foreseeable future.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company follows a <em style="font: inherit;">two</em>-step approach in recognizing and measuring uncertain tax positions. After concluding that a particular filing position can be recognized (i.e., has a more-likely-than-<em style="font: inherit;">not</em> chance of being sustained), ASC <em style="font: inherit;">740</em>-<em style="font: inherit;">10</em>-<em style="font: inherit;">30</em>-<em style="font: inherit;">7</em> requires that the amount of benefit recognized be measured using a methodology based on the concept of cumulative probability. Under this methodology, the amount of benefit recorded represents the largest amount of tax benefit that is greater than <em style="font: inherit;">50%</em> likely to be realized upon settlement with a taxing authority that has full knowledge of all relevant information. See Note <em style="font: inherit;">16</em> for further discussion related to income taxes.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Inventory</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company capitalizes inventory costs related to products to be sold in the ordinary course of business. The Company makes a determination of capitalizing inventory costs for a product based on, among other factors, status of regulatory approval, information regarding safety, efficacy and expectations relating to commercial sales and recoverability of costs. For <i>Jelmyto</i>, the Company commenced capitalization of inventory at the receipt of FDA approval.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company values its inventory at the lower of cost or net realizable value. The Company measures inventory approximating actual cost under a <em style="font: inherit;">first</em>-in, <em style="font: inherit;">first</em>-out basis. The Company assesses recoverability of inventory each reporting period to determine any write down to net realizable value resulting from excess or obsolete inventories<i>.</i></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Property and Equipment</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Property and equipment are recorded at historical cost, net of accumulated depreciation, amortization and, if applicable, impairment charges. The Company reviews its property and equipment assets for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset <em style="font: inherit;"> may </em><em style="font: inherit;">not</em> be recoverable.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Property and equipment are depreciated over the following useful lives (in years):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 10%; margin-left: 10%; width: 80%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 14%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Useful Lives</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Computers and software</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">3</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Laboratory equipment</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">3 - 6.5</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Furniture</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">5 - 16.5</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Manufacturing equipment</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">2 - 10</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Leasehold improvements are amortized on a straight-line basis over the shorter of their estimated useful lives or lease terms. See Note <em style="font: inherit;">8</em> for further discussion regarding property and equipment.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Prepaid Forward Obligation</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company is party to a transaction with RTW Investments (the “RTW Transaction”) in which the Company received funds to support the continued launch of <i>Jelmyto</i> and the development of UGN-<em style="font: inherit;">102</em> in return for tiered, future cash payments based on net sales of <i>Jelmyto</i> and UGN-<em style="font: inherit;">102,</em> if approved by the FDA. The net proceeds received under the RTW Transaction were recognized as a long-term liability. The subsequent measurement for the liability follows the accounting  principles defined in ASC Topic <em style="font: inherit;">835</em>-<em style="font: inherit;">30,</em> “Imputation of Interest”. See Note <em style="font: inherit;">9</em> for further discussion related to the prepaid forward obligation.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Long-Term Debt</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company is party to a loan agreement with funds managed by Pharmakon Advisors, L.P. (“Pharmakon”). The Company recognizes interest expense in current earnings, and accrued interest within other current liabilities on the condensed consolidated balance sheet. The Company recognizes capitalized financing expenses as a direct offset to the long-term debt on the Company's condensed consolidated balance sheet, and amortizes them over the term of the debt using the effective interest method. See Note <em style="font: inherit;">10</em> for further discussion related to long-term debt.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Leases</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company is a lessee in several noncancelable operating leases, primarily for office space, office equipment and vehicles. The Company currently has <em style="font: inherit;">no</em> finance leases.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company accounts for leases in accordance with ASC Topic <em style="font: inherit;">842,</em> “Leases”<i>.</i> The Company determines if an arrangement is a lease at inception. Right-of-use (“ROU”) assets and operating lease liabilities are recognized based on the present value of lease payments over the lease term as of the commencement date. Operating lease ROU assets are presented as operating lease right of use assets on the condensed consolidated balance sheets. The current portion of operating lease liabilities is included in other current liabilities and the long-term portion is presented separately as operating lease liabilities on the condensed consolidated balance sheets.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Lease expense is recognized on a straight-line basis for operating leases. Variable lease payments associated with the Company’s leases are recognized when the event, activity, or circumstance in the lease agreement on which those payments are assessed occurs. Variable lease payments are presented as operating expense on the condensed consolidated statements of operations in the same line item as expense arising from fixed lease payments.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company’s lease terms <em style="font: inherit;"> may </em>include options to extend the lease. The lease extensions are included in the measurement of the right of use asset and lease liability when it is reasonably certain that it will exercise that option.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Because most of the Company’s leases do <em style="font: inherit;">not</em> provide an implicit rate of return, an incremental borrowing rate is used based on the information available at the commencement date in determining the present value of lease payments on an individual lease basis. The Company’s incremental borrowing rate for a lease is the rate of interest it would have to pay on a collateralized basis to borrow an amount equal to the lease payments under similar terms.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">ROU assets for operating leases are periodically reviewed for impairment losses under ASC <em style="font: inherit;">360</em>-<em style="font: inherit;">10,</em> “Property, Plant, and Equipment”, to determine whether an ROU asset is impaired, and if so, the amount of the impairment loss to recognize.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Revenue</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Product sales from <i>Jelmyto</i> are recognized as revenue under ASC <em style="font: inherit;">606</em> at the point in time that control of the product has been transferred to the customer, generally at the point the product has been delivered to the treating physician. All product sales of <i>Jelmyto</i> are recognized through the Company's arrangement with a single customer, a <em style="font: inherit;">third</em>-party national specialty distributor. Net revenue recognized include management’s estimate of returns, consideration paid to the customer, chargebacks relating to differences between the wholesale acquisition cost and the contracted price offered to the end consumer, chargebacks relating to <em style="font: inherit;">340b</em> drug pricing programs, Medicaid drug rebate programs, and the Company’s copay assistance program, which are estimated based on industry benchmarking studies as well as the Company’s historical experience.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Research and Development Expense </i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Research and development costs are expensed as incurred and consist primarily of the cost of salaries, share-based compensation expense, payroll taxes and other employee benefits, subcontractors and materials used for research and development activities, including nonclinical studies, clinical trials, manufacturing costs and professional services. The costs of services performed by others in connection with the research and development activities of the Company, including research and development conducted by others on behalf of the Company, shall be included in research and development costs and expensed as the contracted work is performed. The Company accrues for costs incurred as the services are being provided by monitoring the status of the trial or project and the invoices received from its external service providers. The Company adjusts its accrual as actual costs become known. Where contingent milestone payments are due to <em style="font: inherit;">third</em> parties under research and development arrangements or license agreements, the milestone payment obligations are expensed when such development milestone results are achieved.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Selling</i></b> <b><i>General and Administrative Expense</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Selling, general and administrative expense consists primarily of personnel costs (including share-based compensation related to directors, employees and consultants). Other significant costs include commercial, medical affairs, external professional service costs, facility costs, accounting and audit services, legal services, and other consulting fees. Selling, general and administrative costs are expensed as incurred, and the Company accrues for services provided by <em style="font: inherit;">third</em> parties related to the above expenses by monitoring the status of services provided and receiving estimates from its service providers and adjusting its accruals as actual costs become known.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Share-Based Compensation</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Share-based compensation cost is measured at the grant date based on the fair value of the award and is recognized as expense over the required service period, which is equal to the vesting period. The fair value of options is determined using the Black-Scholes option-pricing model. The fair value of a restricted stock unit (“RSU”) equaled the closing price of the Company’s ordinary shares on the grant date. The Company accounts for forfeitures as they occur in accordance with ASC Topic <em style="font: inherit;">718,</em> “Compensation—Stock Compensation”.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company elected to recognize compensation costs for awards conditioned only on continued service that have a graded vesting schedule using the straight-line method and to value the awards based on the single-option award approach.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Net Loss per Ordinary Share</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Basic net loss per share is computed by dividing the net loss attributable to ordinary shareholders by the weighted-average number of ordinary shares outstanding. Diluted net loss per share is computed similarly to basic net loss per share except that the denominator is increased to include the number of additional ordinary shares that would have been outstanding if the potential ordinary shares had been issued and if the additional ordinary shares were dilutive.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">For all periods presented, potentially dilutive securities are excluded from the computation of fully diluted loss per share as their effect is anti-dilutive.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i/></b></p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Recently Issued Accounting Pronouncements</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company has reviewed the Accounting Standards Updates recently issued by the Financial Accounting Standards Board, and determined that they are <em style="font: inherit;">not</em> applicable to the Company.</p><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"/> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Principles of Consolidation</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The condensed consolidated financial statements include the accounts of UPL and its subsidiary, UPI. Intercompany balances and transactions have been eliminated during consolidation.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Use of Estimates</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenue and expense during the reporting period. Actual results <em style="font: inherit;"> may </em>differ from those estimates. As applicable to the unaudited condensed consolidated financial statements, the critical accounting estimates relate to the fair value of share-based compensation, measurement of revenue, estimate of uncertain tax positions, and measurement of liabilities accounted for under the interest method.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Functional Currency</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The U.S. dollar (“Dollar”) is the currency of the primary economic environment in which the operations of the Company are conducted. Therefore, the functional currency of the Company is the Dollar.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Accordingly, transactions in currencies other than the Dollar are measured and recorded in the functional currency using the exchange rate in effect at the date of the transaction. At the balance sheet date, monetary assets and liabilities that are denominated in currencies other than the Dollar are measured using the official exchange rate at the balance sheet date. The effects of foreign currency re-measurements are recorded in the condensed consolidated statements of operations as “Interest and other income, net.”</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Cash and Cash Equivalents; Marketable Securities</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company considers all highly liquid investments with an original maturity of <em style="font: inherit;">three</em> months or less when purchased to be cash equivalents. Cash and cash equivalents consist primarily of money market funds and bank money market accounts and are stated at cost, which approximates fair value. Restricted cash is related primarily to cash held to secure corporate credit cards; restricted deposits are related to cash held to secure leases.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Cash and cash equivalents and marketable securities totaled $137.1 million as of <em style="font: inherit;"> March 31, 2022</em>. The Company classifies its marketable securities as available-for-sale in accordance with the Financial Accounting Standards Board (“FASB”) Accounting Standards Codification (“ASC”) Topic <em style="font: inherit;">320,</em> “Investments — Debt and Equity Securities”. Available-for-sale debt securities are carried at fair value with unrealized gains and losses reported in other comprehensive income/loss within shareholders’ equity. Realized gains and losses are recorded as a component of interest and other income (expense), net. The cost of securities sold is based on the specific-identification method.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Short-term investments are valued using models or other valuation methodologies that use Level <em style="font: inherit;">2</em> inputs. These models are primarily industry-standard models that consider various assumptions, including time value, yield curve, volatility factors, default rates, current market and contractual prices for the underlying financial instruments, as well as other relevant economic measures. The majority of these assumptions are observable in the marketplace, can be derived from observable data or are supported by observable levels at which transactions are executed in the marketplace. </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">For individual debt securities classified as available-for-sale securities where there has been a decline in fair value below amortized cost, the Company determines whether the decline resulted from a credit loss or other factors. The Company records impairment relating to credit losses through an allowance for credit losses, limited by the amount that the fair value is less than the amortized cost basis. Impairment that has <em style="font: inherit;">not</em> been recorded through an allowance for credit losses is recorded through other comprehensive income, net of applicable taxes.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> 137100000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Concentration of Credit Risk</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Financial instruments, which potentially subject the Company to significant concentrations of credit risk, consist primarily of cash and cash equivalents and marketable securities. The primary objectives for the Company’s investment portfolio are the preservation of capital and the maintenance of liquidity. The Company does <em style="font: inherit;">not</em> enter into any investment transaction for trading or speculative purposes.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company’s investment policy limits investments to certain types of instruments such as certificates of deposit, money market instruments, obligations issued by the U.S. government and U.S. government agencies as well as corporate debt securities, and places restrictions on maturities and concentration by type and issuer. The Company maintains cash balances in excess of amounts insured by the Federal Deposit Insurance Corporation and concentrated within a limited number of financial institutions. The accounts are monitored by management to mitigate the risk.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company’s product sales are recognized through the Company's arrangement with a single customer, a <em style="font: inherit;">third</em>-party national specialty distributor. The Company assesses the need for an allowance for doubtful accounts primarily based on creditworthiness, historical payment experience and general economic conditions. The Company has <em style="font: inherit;">not</em> experienced any credit losses related to this customer and has <em style="font: inherit;">not</em> currently recognized any allowance for doubtful accounts.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: justify; margin: 0pt;"><b><i>Income Taxes</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company provides for income taxes based on pretax income, if any, and applicable tax rates available in the various jurisdictions in which it operates, including Israel and the U.S. deferred taxes are computed using the asset and liability method. Under the asset and liability method, deferred income tax assets and liabilities are determined based on the differences between the financial reporting and tax bases of assets and liabilities and are measured using the currently enacted tax rates and laws. A valuation allowance is recognized to the extent that it is more likely than <em style="font: inherit;">not</em> that the deferred taxes will <em style="font: inherit;">not</em> be realized in the foreseeable future.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company follows a <em style="font: inherit;">two</em>-step approach in recognizing and measuring uncertain tax positions. After concluding that a particular filing position can be recognized (i.e., has a more-likely-than-<em style="font: inherit;">not</em> chance of being sustained), ASC <em style="font: inherit;">740</em>-<em style="font: inherit;">10</em>-<em style="font: inherit;">30</em>-<em style="font: inherit;">7</em> requires that the amount of benefit recognized be measured using a methodology based on the concept of cumulative probability. Under this methodology, the amount of benefit recorded represents the largest amount of tax benefit that is greater than <em style="font: inherit;">50%</em> likely to be realized upon settlement with a taxing authority that has full knowledge of all relevant information. See Note <em style="font: inherit;">16</em> for further discussion related to income taxes.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Inventory</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company capitalizes inventory costs related to products to be sold in the ordinary course of business. The Company makes a determination of capitalizing inventory costs for a product based on, among other factors, status of regulatory approval, information regarding safety, efficacy and expectations relating to commercial sales and recoverability of costs. For <i>Jelmyto</i>, the Company commenced capitalization of inventory at the receipt of FDA approval.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company values its inventory at the lower of cost or net realizable value. The Company measures inventory approximating actual cost under a <em style="font: inherit;">first</em>-in, <em style="font: inherit;">first</em>-out basis. The Company assesses recoverability of inventory each reporting period to determine any write down to net realizable value resulting from excess or obsolete inventories<i>.</i></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Property and Equipment</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Property and equipment are recorded at historical cost, net of accumulated depreciation, amortization and, if applicable, impairment charges. The Company reviews its property and equipment assets for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset <em style="font: inherit;"> may </em><em style="font: inherit;">not</em> be recoverable.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Property and equipment are depreciated over the following useful lives (in years):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 10%; margin-left: 10%; width: 80%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 14%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Useful Lives</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Computers and software</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">3</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Laboratory equipment</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">3 - 6.5</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Furniture</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">5 - 16.5</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Manufacturing equipment</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">2 - 10</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Leasehold improvements are amortized on a straight-line basis over the shorter of their estimated useful lives or lease terms. See Note <em style="font: inherit;">8</em> for further discussion regarding property and equipment.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 10%; margin-left: 10%; width: 80%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 14%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Useful Lives</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Computers and software</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">3</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Laboratory equipment</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">3 - 6.5</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Furniture</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">5 - 16.5</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 84%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Manufacturing equipment</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 14%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: center;">2 - 10</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> </tbody></table> P3Y P3Y P6Y6M P5Y P16Y6M P2Y P10Y <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Prepaid Forward Obligation</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company is party to a transaction with RTW Investments (the “RTW Transaction”) in which the Company received funds to support the continued launch of <i>Jelmyto</i> and the development of UGN-<em style="font: inherit;">102</em> in return for tiered, future cash payments based on net sales of <i>Jelmyto</i> and UGN-<em style="font: inherit;">102,</em> if approved by the FDA. The net proceeds received under the RTW Transaction were recognized as a long-term liability. The subsequent measurement for the liability follows the accounting  principles defined in ASC Topic <em style="font: inherit;">835</em>-<em style="font: inherit;">30,</em> “Imputation of Interest”. See Note <em style="font: inherit;">9</em> for further discussion related to the prepaid forward obligation.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Long-Term Debt</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company is party to a loan agreement with funds managed by Pharmakon Advisors, L.P. (“Pharmakon”). The Company recognizes interest expense in current earnings, and accrued interest within other current liabilities on the condensed consolidated balance sheet. The Company recognizes capitalized financing expenses as a direct offset to the long-term debt on the Company's condensed consolidated balance sheet, and amortizes them over the term of the debt using the effective interest method. See Note <em style="font: inherit;">10</em> for further discussion related to long-term debt.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Leases</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company is a lessee in several noncancelable operating leases, primarily for office space, office equipment and vehicles. The Company currently has <em style="font: inherit;">no</em> finance leases.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company accounts for leases in accordance with ASC Topic <em style="font: inherit;">842,</em> “Leases”<i>.</i> The Company determines if an arrangement is a lease at inception. Right-of-use (“ROU”) assets and operating lease liabilities are recognized based on the present value of lease payments over the lease term as of the commencement date. Operating lease ROU assets are presented as operating lease right of use assets on the condensed consolidated balance sheets. The current portion of operating lease liabilities is included in other current liabilities and the long-term portion is presented separately as operating lease liabilities on the condensed consolidated balance sheets.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Lease expense is recognized on a straight-line basis for operating leases. Variable lease payments associated with the Company’s leases are recognized when the event, activity, or circumstance in the lease agreement on which those payments are assessed occurs. Variable lease payments are presented as operating expense on the condensed consolidated statements of operations in the same line item as expense arising from fixed lease payments.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company’s lease terms <em style="font: inherit;"> may </em>include options to extend the lease. The lease extensions are included in the measurement of the right of use asset and lease liability when it is reasonably certain that it will exercise that option.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Because most of the Company’s leases do <em style="font: inherit;">not</em> provide an implicit rate of return, an incremental borrowing rate is used based on the information available at the commencement date in determining the present value of lease payments on an individual lease basis. The Company’s incremental borrowing rate for a lease is the rate of interest it would have to pay on a collateralized basis to borrow an amount equal to the lease payments under similar terms.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">ROU assets for operating leases are periodically reviewed for impairment losses under ASC <em style="font: inherit;">360</em>-<em style="font: inherit;">10,</em> “Property, Plant, and Equipment”, to determine whether an ROU asset is impaired, and if so, the amount of the impairment loss to recognize.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Revenue</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Product sales from <i>Jelmyto</i> are recognized as revenue under ASC <em style="font: inherit;">606</em> at the point in time that control of the product has been transferred to the customer, generally at the point the product has been delivered to the treating physician. All product sales of <i>Jelmyto</i> are recognized through the Company's arrangement with a single customer, a <em style="font: inherit;">third</em>-party national specialty distributor. Net revenue recognized include management’s estimate of returns, consideration paid to the customer, chargebacks relating to differences between the wholesale acquisition cost and the contracted price offered to the end consumer, chargebacks relating to <em style="font: inherit;">340b</em> drug pricing programs, Medicaid drug rebate programs, and the Company’s copay assistance program, which are estimated based on industry benchmarking studies as well as the Company’s historical experience.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Research and Development Expense </i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Research and development costs are expensed as incurred and consist primarily of the cost of salaries, share-based compensation expense, payroll taxes and other employee benefits, subcontractors and materials used for research and development activities, including nonclinical studies, clinical trials, manufacturing costs and professional services. The costs of services performed by others in connection with the research and development activities of the Company, including research and development conducted by others on behalf of the Company, shall be included in research and development costs and expensed as the contracted work is performed. The Company accrues for costs incurred as the services are being provided by monitoring the status of the trial or project and the invoices received from its external service providers. The Company adjusts its accrual as actual costs become known. Where contingent milestone payments are due to <em style="font: inherit;">third</em> parties under research and development arrangements or license agreements, the milestone payment obligations are expensed when such development milestone results are achieved.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Selling</i></b> <b><i>General and Administrative Expense</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Selling, general and administrative expense consists primarily of personnel costs (including share-based compensation related to directors, employees and consultants). Other significant costs include commercial, medical affairs, external professional service costs, facility costs, accounting and audit services, legal services, and other consulting fees. Selling, general and administrative costs are expensed as incurred, and the Company accrues for services provided by <em style="font: inherit;">third</em> parties related to the above expenses by monitoring the status of services provided and receiving estimates from its service providers and adjusting its accruals as actual costs become known.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Share-Based Compensation</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Share-based compensation cost is measured at the grant date based on the fair value of the award and is recognized as expense over the required service period, which is equal to the vesting period. The fair value of options is determined using the Black-Scholes option-pricing model. The fair value of a restricted stock unit (“RSU”) equaled the closing price of the Company’s ordinary shares on the grant date. The Company accounts for forfeitures as they occur in accordance with ASC Topic <em style="font: inherit;">718,</em> “Compensation—Stock Compensation”.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company elected to recognize compensation costs for awards conditioned only on continued service that have a graded vesting schedule using the straight-line method and to value the awards based on the single-option award approach.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Net Loss per Ordinary Share</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Basic net loss per share is computed by dividing the net loss attributable to ordinary shareholders by the weighted-average number of ordinary shares outstanding. Diluted net loss per share is computed similarly to basic net loss per share except that the denominator is increased to include the number of additional ordinary shares that would have been outstanding if the potential ordinary shares had been issued and if the additional ordinary shares were dilutive.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">For all periods presented, potentially dilutive securities are excluded from the computation of fully diluted loss per share as their effect is anti-dilutive.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Recently Issued Accounting Pronouncements</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company has reviewed the Accounting Standards Updates recently issued by the Financial Accounting Standards Board, and determined that they are <em style="font: inherit;">not</em> applicable to the Company.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">4</em> </b>–<b> Other Financial Information</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Accounts Payable and Accrued Expense</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Accounts payable and accrued expense consists of the following as of <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;"> December </em><em style="font: inherit;">31,</em> <em style="font: inherit;">2021</em> (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 10%; margin-left: 10%; width: 80%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 66%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accounts payable</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">4,234</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,786</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accrued sales reserves</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">361</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">497</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accrued clinical expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,129</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,377</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accrued research and development expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,186</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,748</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accrued selling, general and administrative expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">2,042</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,965</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accrued other expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">984</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">729</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total accounts payable and accrued expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">9,936</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">12,102</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Interest and Other Income (Expense), Net</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Interest and other income (expense) consisted of the following as of <em style="font: inherit;"> March 31, 2022 </em>and <em style="font: inherit;">2021</em> (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 10%; margin-left: 10%; width: 80%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Three Months Ended March 31,</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 66%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Interest income</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">2</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">167</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Other finance (expense), net</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">(4</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">12</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total other income (expense)</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">(2</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">179</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 10%; margin-left: 10%; width: 80%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 66%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accounts payable</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">4,234</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,786</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accrued sales reserves</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">361</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">497</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accrued clinical expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,129</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,377</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accrued research and development expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,186</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,748</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accrued selling, general and administrative expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">2,042</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,965</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Accrued other expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">984</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">729</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total accounts payable and accrued expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">9,936</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">12,102</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> 4234000 5786000 361000 497000 1129000 1377000 1186000 1748000 2042000 1965000 984000 729000 9936000 12102000 <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 10%; margin-left: 10%; width: 80%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Three Months Ended March 31,</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 66%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Interest income</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">2</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">167</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Other finance (expense), net</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">(4</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">12</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total other income (expense)</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">(2</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">179</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> 2000 167000 -4000 12000 -2000 179000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">5</em> </b>–<b> Inventories</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Inventories consist of the following as of <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;"> December 31, 2021</em> (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 10%; margin-left: 10%; width: 80%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 66%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Raw materials <sup style="vertical-align:top;line-height:120%;font-size:pt">(1)</sup></p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">3,663</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">3,894</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Finished goods</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,365</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">1,958</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total inventories</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">6,028</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">5,852</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 100%; margin-left: auto; margin-right: auto;"> <tbody> <tr style="font-family: Arial, Helvetica, sans-serif;"> <td style="vertical-align: top; width: 2%; font-family: Arial, Helvetica, sans-serif;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> </td> <td style="vertical-align: top; width: auto; font-family: Arial, Helvetica, sans-serif;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><sup style="vertical-align:top;line-height:120%;font-size:pt">(<em style="font: inherit;">1</em>)</sup> $1.3 million and $1.0 million of raw materials are included within other non-current assets on the condensed consolidated balance sheets at <em style="font: inherit;"> March 31, 2022 </em>and <em style="font: inherit;"> December 31, 2021, </em>respectively .</p> </td> </tr> </tbody> </table> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 10%; margin-left: 10%; width: 80%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 66%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Raw materials <sup style="vertical-align:top;line-height:120%;font-size:pt">(1)</sup></p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">3,663</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">3,894</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Finished goods</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,365</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">1,958</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total inventories</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">6,028</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 14%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">5,852</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> 3663000 3894000 2365000 1958000 6028000 5852000 1300000 1000000.0 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">6</em> </b>–<b> Fair Value Measurements</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company follows authoritative accounting guidance, which among other things, defines fair value, establishes a consistent framework for measuring fair value and expands disclosure for each major asset and liability category measured at fair value on either a recurring or nonrecurring basis. Fair value is an exit price, representing the amount that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants. As such, fair value is a market-based measurement that should be determined based on assumptions that market participants would use in pricing an asset or liability.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">As a basis for considering such assumptions, a <em style="font: inherit;">three</em>-tier fair value hierarchy has been established, which prioritizes the inputs used in measuring fair value as follows:</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 100%; margin-left: auto; margin-right: auto;"> <tbody> <tr style="font-family: Arial, Helvetica, sans-serif;"> <td style="vertical-align: top; width: 1%; font-family: Arial, Helvetica, sans-serif;"> </td> <td style="vertical-align: top; width: 10%; font-family: Arial, Helvetica, sans-serif;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Level <em style="font: inherit;">1:</em></p> </td> <td style="vertical-align: top; width: 89%; font-family: Arial, Helvetica, sans-serif;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Observable inputs such as quoted prices (unadjusted) in active markets for identical assets or liabilities.</p> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 100%; margin-left: auto; margin-right: auto;"> <tbody> <tr style="font-family: Arial, Helvetica, sans-serif;"> <td style="vertical-align: top; width: 1%; font-family: Arial, Helvetica, sans-serif;"> </td> <td style="vertical-align: top; width: 10%; font-family: Arial, Helvetica, sans-serif;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Level <em style="font: inherit;">2:</em></p> </td> <td style="vertical-align: top; width: 89%; font-family: Arial, Helvetica, sans-serif;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Inputs other than quoted prices that are observable for the asset or liability, either directly or indirectly. These include quoted prices for similar assets or liabilities in active markets and quoted prices for identical or similar assets or liabilities in markets that are <em style="font: inherit;">not</em> active.</p> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 100%; margin-left: auto; margin-right: auto;"> <tbody> <tr style="font-family: Arial, Helvetica, sans-serif;"> <td style="vertical-align: top; width: 1%; font-family: Arial, Helvetica, sans-serif;"> </td> <td style="vertical-align: top; width: 10%; font-family: Arial, Helvetica, sans-serif;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Level <em style="font: inherit;">3:</em></p> </td> <td style="vertical-align: top; width: 89%; font-family: Arial, Helvetica, sans-serif;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Unobservable inputs that reflect the reporting entity’s own assumptions.</p> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The carrying amounts of the Company’s cash and cash equivalents, restricted cash, other current assets, accounts payable and accrued liabilities are generally considered to be representative of their fair value because of the short-term nature of these instruments. The carrying value of the prepaid forward obligation (See Note <em style="font: inherit;">9</em> - Prepaid Forward Obligation) approximates its fair value as the effective interest rate approximates the market rate for loans with similar terms and risk characteristics. Likewise, the carrying value of long-term debt on the Company’s balance sheet (see Note <em style="font: inherit;">10</em> – Long-Term Debt), approximates its fair value as the interest rate approximates the market rate for loans with similar terms and risk characteristics. <em style="font: inherit;">No</em> transfers between levels have occurred during the periods presented.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Assets and liabilities measured at fair value on a recurring basis based on Level <em style="font: inherit;">1</em> and Level <em style="font: inherit;">2</em> fair value measurement criteria as of <em style="font: inherit;"> March 31, 2022</em> are as follows (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 2.5%; margin-left: 2.5%; width: 95%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: thin solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Fair Value Measurements Using</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Quoted Prices</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Significant</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">in Active</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Other</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Balance as of</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Markets for</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Observable</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Identical Assets</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Inputs</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">(Level 1)</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">(Level 2)</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 55%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Marketable securities:</p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">US government</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,251</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,251</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Corporate bonds</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,296</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,296</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Commercial paper</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,192</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,192</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Certificates of deposit</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,000</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right; border-bottom: 1px solid rgb(0, 0, 0);"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,000</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total marketable securities</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">31,739</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">19,251</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">12,488</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 19pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 19pt;">Additionally, as of <em style="font: inherit;"> March 31, 2022 </em>there were approximately $75.0 million of money market funds included within cash and cash equivalents on the condensed consolidated balance sheet that are measured at fair value based on Level <em style="font: inherit;">1</em> fair value measurement criteria.</p> <table border="0" cellpadding="0" cellspacing="0" style="width: 100%; text-indent: 0px;"> <tbody> <tr style="vertical-align: top;"> <td style="width: 18pt;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> </td> <td style="width: auto;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> </td> </tr> </tbody> </table> <table border="0" cellpadding="0" cellspacing="0" style="width: 100%; text-indent: 0px;"> <tbody> <tr style="vertical-align: top;"> <td style="width: 18pt;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> </td> <td style="width: auto;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Assets and liabilities measured at fair value on a recurring basis based on Level <em style="font: inherit;">1</em> and Level <em style="font: inherit;">2</em> fair value measurement criteria as of <em style="font: inherit;"> December 31, 2021</em> are as follows (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 2.5%; margin-left: 2.5%; width: 95%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: thin solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Fair Value Measurements Using</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Quoted Prices</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Significant</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">in Active</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Other</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Balance as of</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Markets for</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Observable</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Identical Assets</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Inputs</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">(Level 1)</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">(Level 2)</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 55%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Marketable securities:</p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">US government</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,307</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,307</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">—</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Corporate bonds</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">8,652</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right;">—</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">8,652</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> <p style="margin-top: 0pt; margin-bottom: 0pt">Commercial paper</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">14,492</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">—</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">14,492</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> <p style="margin-top: 0pt; margin-bottom: 0pt">Certificates of deposit</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);">3,003</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);">—</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);">3,003</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total marketable securities</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">45,454</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">19,307</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">26,147</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Additionally, as of <em style="font: inherit;"> December 31, 2021 </em>there were approximately $21.4 million of money market funds included within cash and cash equivalents on the condensed consolidated balance sheet that are measured at fair value based on Level <em style="font: inherit;">1</em> fair value measurement criteria.</p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 2.5%; margin-left: 2.5%; width: 95%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: thin solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Fair Value Measurements Using</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Quoted Prices</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Significant</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">in Active</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Other</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Balance as of</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Markets for</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Observable</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Identical Assets</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Inputs</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">(Level 1)</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">(Level 2)</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 55%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Marketable securities:</p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">US government</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,251</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,251</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Corporate bonds</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,296</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,296</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Commercial paper</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,192</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,192</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Certificates of deposit</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,000</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right; border-bottom: 1px solid rgb(0, 0, 0);"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,000</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total marketable securities</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">31,739</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">19,251</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">12,488</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 2.5%; margin-left: 2.5%; width: 95%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: thin solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Fair Value Measurements Using</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Quoted Prices</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Significant</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">in Active</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Other</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Balance as of</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Markets for</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Observable</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Identical Assets</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Inputs</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">(Level 1)</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">(Level 2)</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 55%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Marketable securities:</p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">US government</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,307</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,307</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">—</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Corporate bonds</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">8,652</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right;">—</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">8,652</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> <p style="margin-top: 0pt; margin-bottom: 0pt">Commercial paper</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">14,492</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">—</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">14,492</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> <p style="margin-top: 0pt; margin-bottom: 0pt">Certificates of deposit</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);">3,003</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);">—</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0px; margin: 0px; border-bottom: 1px solid rgb(0, 0, 0);">3,003</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total marketable securities</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">45,454</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">19,307</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">26,147</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> 19251000 19251000 5296000 5296000 5192000 5192000 2000000 2000000 31739000 19251000 12488000 75000000.0 19307000 19307000 0 8652000 0 8652000 14492000 0 14492000 3003000 0 3003000 45454000 19307000 26147000 21400000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">7</em> </b>–<b> Marketable Securities</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The following table summarizes the Company’s marketable securities (excluding cash and cash equivalents) as of <em style="font: inherit;"> March 31, 2022</em> (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 2.5%; margin-left: 2.5%; width: 95%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Amortized</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Unrealized</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Unrealized</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Cost Basis</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Gains</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Losses</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Fair Value</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 48%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Marketable securities:</p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">US government</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,302</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">(51</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,251</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Corporate bonds</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,305</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right;">(9</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,296</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Commercial paper</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,198</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">(6</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,192</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Certificates of deposit</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,003</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 10%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right; border-bottom: 1px solid rgb(0, 0, 0);"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">(3</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,000</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total marketable securities</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">31,808</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">—</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">(69</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 3px;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">31,739</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" style="width: 100%; text-indent: 0px;"> <tbody> <tr style="vertical-align: top;"> <td style="width: 18pt;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> </td> <td style="width: auto;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> </td> </tr> </tbody> </table> <table border="0" cellpadding="0" cellspacing="0" style="width: 100%; text-indent: 0px;"> <tbody> <tr style="vertical-align: top;"> <td style="width: 18pt;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> </td> <td style="width: auto;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company classifies its marketable securities as available-for-sale and they consist of all debt securities. The amortized cost basis as of <em style="font: inherit;"> March 31, 2022</em> includes $0.1 million of accrued interest receivable. As of <em style="font: inherit;"> March 31, 2022</em> marketable securities were in a net unrealized loss position. Unrealized gains and losses on available-for-sale debt securities are included as a component of comprehensive loss. </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">As of <em style="font: inherit;"> March 31, 2022</em>, the aggregate fair value of marketable securities held by the Company in an unrealized loss position was $31.7 million which consisted of <em style="font: inherit;">17</em> securities. The unrealized loss was primarily driven by minor fluctuations in the fair value of corporate bonds driven by changes in market interest rates. The Company does <em style="font: inherit;">not</em> expect to settle the debentures at a price less than the amortized cost basis of the investment; the Company expects to recover the entire amortized cost basis of the security. In accordance with the Company’s general investment strategy, the Company does <em style="font: inherit;">not</em> intend to sell the investments before maturity. As of <em style="font: inherit;"> March 31, 2022</em>, the Company believes the cost basis for its marketable securities were recoverable in all material aspects and <em style="font: inherit;">no</em> credit losses were recognized in the period.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company’s marketable securities as of <em style="font: inherit;"> March 31, 2022</em> mature at various dates through <em style="font: inherit;"> July 2023. </em>The fair values of marketable securities by contractual maturity consist of the following (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Maturities within one year</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">31,065</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">44,779</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Maturities after one year through three years</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">674</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">675</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total marketable securities</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">31,739</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">45,454</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="margin: 0pt; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </p> <p style="margin: 0pt; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 2.5%; margin-left: 2.5%; width: 95%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Amortized</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Unrealized</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Unrealized</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em></td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><b> </b></td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Cost Basis</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Gains</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Losses</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Fair Value</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 48%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Marketable securities:</p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">US government</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,302</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">(51</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">19,251</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Corporate bonds</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,305</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right;">(9</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,296</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Commercial paper</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,198</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right;"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">(6</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5,192</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Certificates of deposit</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,003</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 10%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; text-align: right; border-bottom: 1px solid rgb(0, 0, 0);"></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">(3</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,000</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total marketable securities</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">31,808</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">—</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">(69</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 3px;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">31,739</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> 19302000 51000 19251000 5305000 9000 5296000 5198000 6000 5192000 2003000 3000 2000000 31808000 0 69000 31739000 100000 31700000 <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Maturities within one year</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">31,065</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">44,779</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Maturities after one year through three years</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">674</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">675</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Total marketable securities</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">31,739</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">45,454</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> 31065000 44779000 674000 675000 31739000 45454000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">8</em> </b>–<b> Property and Equipment</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Property and equipment, consists of the following as of <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;"> December 31, 2021</em> (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Laboratory equipment</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">374</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">360</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Computer equipment and software</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">2,072</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">2,064</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Furniture</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">597</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">597</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Leasehold improvements</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">617</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">617</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Manufacturing equipment</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">558</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">555</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">4,218</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">4,193</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Less: accumulated depreciation and amortization</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">(2,441</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">(2,226</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;">)</td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Property and equipment, net</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">1,777</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">1,967</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Depreciation and amortization expense was $0.2 million for the <em style="font: inherit;">three</em> months ended <em style="font: inherit;"> March 31, 2022</em> and $0.2 million for the <em style="font: inherit;">three</em> months ended <em style="font: inherit;"> March 31, 2021</em>.</p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Laboratory equipment</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">374</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">360</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Computer equipment and software</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">2,072</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">2,064</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Furniture</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">597</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">597</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Leasehold improvements</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">617</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">617</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Manufacturing equipment</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">558</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">555</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">4,218</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">4,193</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Less: accumulated depreciation and amortization</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">(2,441</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;">)</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">(2,226</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;">)</td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Property and equipment, net</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">1,777</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">1,967</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> 374000 360000 2072000 2064000 597000 597000 617000 617000 558000 555000 4218000 4193000 2441000 2226000 1777000 1967000 200000 200000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">9</em> </b>–<b> Prepaid Forward Obligation</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> March 2021, </em>the Company entered into a prepaid forward agreement with RTW Investments (“RTW”). Under the terms of the RTW Transaction, the Company received $75.0 million (<span style="background-color:#ffffff;">$72.4</span> million net of transaction costs) to support the continued launch of <i>Jelmyto</i> and the development of UGN-<em style="font: inherit;">102.</em> In return for the transferred funds, RTW is entitled to receive tiered, future cash payments based on aggregate worldwide annual net product sales of <i>Jelmyto</i> in an amount equal to: (i) 9.5% of annual net sales up to <em style="font: inherit;">$200</em> million, (ii) 3.0% of annual net sales for annual net sales between <em style="font: inherit;">$200</em> million and <em style="font: inherit;">$300</em> million, and (iii) 1.0% of annual net sales for annual net sales above <em style="font: inherit;">$300</em> million. If certain revenue thresholds for <i>Jelmyto</i> aggregate worldwide annual net sales are <em style="font: inherit;">not</em> met, the future cash payments to RTW with respect to <i>Jelmyto</i> annual net sales up to <em style="font: inherit;">$200</em> million will increase by 3.5%, and <em style="font: inherit;"> may </em>decrease back to <em style="font: inherit;">9.5%</em> dependent on the Company meeting certain subsequent <i>Jelmyto</i> aggregate worldwide annual net sales thresholds. The rate in effect for the <em style="font: inherit;">three</em> months ended <em style="font: inherit;"> March 31, 2022 </em>for annual sales up to $200 million was 13.0%.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In addition, subject to FDA approval of UGN-<em style="font: inherit;">102,</em> RTW is entitled to receive tiered, future cash payments based on aggregate worldwide annual net product sales of UGN-<em style="font: inherit;">102</em> in an amount equal to: (i) 2.5% of annual net sales up to <em style="font: inherit;">$200</em> million, (ii) 1.0% of annual net sales for annual net sales between <em style="font: inherit;">$200</em> million and <em style="font: inherit;">$300</em> million, and (iii) 0.5% of annual net sales for annual net sales above <em style="font: inherit;">$300</em> million. If the Company does <em style="font: inherit;">not</em> receive FDA approval for UGN-<em style="font: inherit;">102</em> by a specified date, the future cash payments to RTW with respect to aggregate worldwide annual net sales of <i>Jelmyto</i> across all <i>Jelmyto</i> annual net sales tiers will increase by 1.5%. The rate in effect for <em style="font: inherit;">2022</em> for sales up to $200 million is 13%. </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In accordance with the prepaid forward agreement, the Company will be required to make payments of amounts owed to RTW each calendar quarter, through and until the quarter in which the aggregate cash payments received by RTW are equal to or greater than <em style="font: inherit;">$300</em> million. As security for the payment and fulfilment of these amounts throughout the arrangement, the Company has granted RTW a <em style="font: inherit;">first</em> priority security interest in <i>Jelmyto</i> and UGN-<em style="font: inherit;">102,</em> including the regulatory approvals, intellectual property, material agreements, proceeds and accounts receivable related to these products.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> May 2021</em><i>,</i> following the receipt of necessary regulatory approvals, the Company received the $75.0 million prepaid forward payment ($72.4 million net of transaction costs) from RTW and recognized an associated prepaid forward obligation liability. Each period the Company makes a payment to RTW, an expense is recognized related to financing on the prepaid forward obligation based on an imputed rate derived from the expected future payments. Management reassesses the effective rate each period based on the current carrying value of the obligation and the revised estimated future payments. Changes in future payments from previous estimates are included in current and future financing expense. The Company does <span style="-sec-ix-hidden:c84038839">not</span> expect to make any principal payments in the next <em style="font: inherit;">12</em> months.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The following table shows the activity with respect to the carrying value of the prepaid forward liability, in thousands:</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 87%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Prepaid forward obligation at closing of RTW Transaction</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038842">75,000</span></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Capitalized closing costs</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">(2,599</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Financing on prepaid forward obligation</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">17,291</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Amounts paid and payable</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">(3,979</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;">)</td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> <p style="margin-top: 0pt; margin-bottom: 0pt">Carrying value of prepaid forward obligation as of December 31, 2021</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">85,713</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> <p style="margin-top: 0pt; margin-bottom: 0pt">Financing on prepaid forward obligation</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">5,826</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> <p style="margin-top: 0pt; margin-bottom: 0pt">Amounts paid and payable</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">(1,757</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">)</td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Carrying value of prepaid forward obligation as of March 31, 2022</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">89,782</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> 75000000.0 72400000 0.095 0.030 0.010 0.035 200000000 0.130 0.025 0.010 0.005 0.015 200000000 0.13 75000000.0 72400000 <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 87%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Prepaid forward obligation at closing of RTW Transaction</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038842">75,000</span></td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Capitalized closing costs</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">(2,599</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Financing on prepaid forward obligation</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">17,291</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Amounts paid and payable</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">(3,979</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; padding-bottom: 1px;">)</td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> <p style="margin-top: 0pt; margin-bottom: 0pt">Carrying value of prepaid forward obligation as of December 31, 2021</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">85,713</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> <p style="margin-top: 0pt; margin-bottom: 0pt">Financing on prepaid forward obligation</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">5,826</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> <p style="margin-top: 0pt; margin-bottom: 0pt">Amounts paid and payable</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0"> </td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">(1,757</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding: 0; margin: 0">)</td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Carrying value of prepaid forward obligation as of March 31, 2022</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 10%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">89,782</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> 2599000 17291000 3979000 85713000 5826000 1757000 89782000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">10</em> – Long-Term Debt</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">On <em style="font: inherit;"> March 7, </em><em style="font: inherit;">2022,</em> the Company entered into a loan agreement with Pharmakon for a senior secured term loan of up to $100 million in <em style="font: inherit;">two</em> tranches. The <em style="font: inherit;">first</em> tranche of $75 million was funded in <em style="font: inherit;"> March 2022. </em>At its option, the Company <em style="font: inherit;"> may </em>draw up to an additional $25 million before <em style="font: inherit;"> December 31, 2022, </em>subject to customary bring down conditions and deliverables. The facility will mature <span style="-sec-ix-hidden:c84038857">five</span> years from initial funding and can be prepaid in whole at the Company's discretion, at any time, subject to prepayment premiums and makewhole amounts. The loan will require interest-only payments for the <em style="font: inherit;">first</em> <em style="font: inherit;">48</em> months followed by principal and interest payments with interest accruing using <em style="font: inherit;">3</em>-month London Inter-Bank Offered Rate (“LIBOR”) (with a 1.25% floor) plus 8.25%. In the event of the cessation of LIBOR, the benchmark governing the interest rate will be replaced with a rate based on the secured overnight financing rate published by the Federal Reserve Bank of New York. The Company is <em style="font: inherit;">not</em> required to maintain any financial covenants.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company incurred financing expenses of $4.2 million which are recognized as a direct offset to the long-term debt on the Company's condensed consolidated balance sheet. These debt issuance costs are  amortized over the term of the debt using the effective interest method, and are recorded in the condensed consolidated statements of operations as “Interest expense".</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The following table shows the activity with respect to the carrying value of the long-term debt, in thousands:</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 62%; margin-left: 19%; margin-right: 19%;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="vertical-align: bottom; width: 83.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Long-term debt at closing of Pharmakon loan</p> </td> <td style="vertical-align: bottom; width: 16.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038865">$ 75,000</span></p> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="vertical-align: bottom; width: 83.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Capitalized costs and discounts</p> </td> <td style="vertical-align: bottom; width: 16.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038866">(4,169)</span></p> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="vertical-align: bottom; width: 83.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Interest expense</p> </td> <td style="vertical-align: bottom; width: 16.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">282</p> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="vertical-align: bottom; width: 83.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Amounts paid and payable</p> </td> <td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 16.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038868">(316)</span></p> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="vertical-align: bottom; width: 83.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Carrying value of Pharmakon loan as of March 31, 2022</p> </td> <td style="vertical-align: bottom; width: 16.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">70,797</p> </td> </tr> </tbody> </table> 100000000 75000000 25000000 0.0125 0.0825 4200000 <table cellpadding="0" cellspacing="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 62%; margin-left: 19%; margin-right: 19%;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="vertical-align: bottom; width: 83.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Long-term debt at closing of Pharmakon loan</p> </td> <td style="vertical-align: bottom; width: 16.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038865">$ 75,000</span></p> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="vertical-align: bottom; width: 83.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Capitalized costs and discounts</p> </td> <td style="vertical-align: bottom; width: 16.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038866">(4,169)</span></p> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="vertical-align: bottom; width: 83.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Interest expense</p> </td> <td style="vertical-align: bottom; width: 16.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">282</p> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="vertical-align: bottom; width: 83.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Amounts paid and payable</p> </td> <td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 16.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038868">(316)</span></p> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="vertical-align: bottom; width: 83.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Carrying value of Pharmakon loan as of March 31, 2022</p> </td> <td style="vertical-align: bottom; width: 16.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">70,797</p> </td> </tr> </tbody> </table> 282000 70797000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">11</em> </b>–<b> Leases </b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Operating Leases</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company has the following office and laboratory facility leases:</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" style="width: 100%; text-indent: 0px;"><tbody><tr style="vertical-align: top;"><td style="width: 18pt;"> </td><td style="width: 18pt;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;">•</p> </td><td style="width: auto;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> April 2016, </em>UPL signed an addendum to its <em style="font: inherit;"> November 2014 </em>lease agreement for the Company’s offices located in Israel, in order to increase the office space rented and to extend the rent period until <em style="font: inherit;">2019.</em> In <em style="font: inherit;"> March 2019, </em>UPL utilized the agreement extension option and extended the rent period for additional <em style="font: inherit;">three</em> years until <em style="font: inherit;"> August 2022.</em></p> </td></tr> </tbody></table> <p style="margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" style="width: 100%; text-indent: 0px;"><tbody><tr style="vertical-align: top;"><td style="width: 18pt;"> </td><td style="width: 18pt;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;">•</p> </td><td style="width: auto;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> September 2017, </em>UPI entered into a new lease agreement for its office space in New York, which the Company previously used as its headquarters. The lease agreement commenced in <em style="font: inherit;"> October 2017 </em>and terminated in <em style="font: inherit;"> February 2021.  </em></p> </td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" style="width: 100%; text-indent: 0px;"><tbody><tr style="vertical-align: top;"><td style="width: 18pt;"> </td><td style="width: 18pt;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;">•</p> </td><td style="width: auto;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> April 2018, </em>UPI entered into a new lease agreement for an office in Los Angeles, California. The lease commencement date was <em style="font: inherit;"> July 10, 2018 </em>and terminates in <em style="font: inherit;"> March 2024. </em>The landlord provided a tenant allowance for leasehold improvements of $0.2 million that was accounted for as a lease incentive. The Company’s remaining contractual obligation under this lease is approximately $0.6 million as of <em style="font: inherit;"> March 31, 2022</em>. In <em style="font: inherit;"> November 2019, </em>UPI entered into a sublease for this office space, with a lease commencement date of <em style="font: inherit;"> January 1, 2020 </em>and continuing until the end of the lease term in <em style="font: inherit;"> March 2024. </em>The subtenants exercised their early access clause and moved into the premises at the end of <em style="font: inherit;"> November 2019. </em>The remaining rental payments to be received over the lease term is approximately $0.5 million as of <em style="font: inherit;"> March 31, 2022</em>. The Company accounts for the sublease as on operating lease in accordance with ASC <em style="font: inherit;">842</em>-<em style="font: inherit;">10</em>-<em style="font: inherit;">25</em>-<em style="font: inherit;">2</em> and ASC <em style="font: inherit;">842</em>-<em style="font: inherit;">10</em>-<em style="font: inherit;">25</em>-<em style="font: inherit;">3.</em> The main lease was considered for impairment and the amount was determined to be immaterial.</p> </td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" style="width: 100%; text-indent: 0px;"><tbody><tr style="vertical-align: top;"><td style="width: 18pt;"> </td><td style="width: 18pt;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;">•</p> </td><td style="width: auto;"> <p style="font-family: Arial; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> November 2019, </em>UPI entered into a new lease agreement for an office in Princeton, New Jersey, which the Company now uses as its headquarters. The lease commencement date was <em style="font: inherit;"> November 29, 2019 </em>and the lease term is 38 months. The Company’s remaining contractual obligation under this lease is approximately $0.5 million as of <em style="font: inherit;"> March 31, 2022</em>.</p> </td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In addition, the Company has other operating office equipment and vehicle leases. The Company’s operating leases <em style="font: inherit;"> may </em>require minimum rent payments, contingent rent payments adjusted periodically for inflation, or rent payments equal to the greater of a minimum rent or contingent rent. The Company’s leases do <em style="font: inherit;">not</em> contain any residual value guarantees or material restrictive covenants. The Company’s leases expire at various dates from <em style="font: inherit;">2022</em> through <em style="font: inherit;">2024,</em> with varying renewal and termination options.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The components of lease cost for the <em style="font: inherit;">three</em> months ended <em style="font: inherit;"> March 31, 2022</em>  and <em style="font: inherit;">2021</em> were as follows (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Three Months Ended</em></em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">March 31,</em></em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Operating lease cost</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">259</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">267</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Sublease income</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">(56</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">(56</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Variable lease cost</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">17</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">22</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">220</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">233</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The amounts recognized as of <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;"> December 31, 2021</em> were as follows (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Right of use asset</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">945</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,180</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Long-term lease liabilities</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">277</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">398</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Other current liabilities</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">930</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,089</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">As of <em style="font: inherit;"> March 31, 2022</em>, <em style="font: inherit;">no</em> impairment losses have been recognized to date.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Supplemental information related to leases for the <em style="font: inherit;">three</em> months ended <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;">2021</em> is as follows (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p>   <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><b>Three Months Ended</b></td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><b>March 31,</b></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><b>2022</b></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><b>2021</b></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; background-color: rgb(204, 238, 255);"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Cash paid for amounts included in the measurement of lease liabilities:</p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; background-color: rgb(255, 255, 255);"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt; margin-left: 9pt;">Operating cash flows from operating leases</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">3,322</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">2,157</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; background-color: rgb(204, 238, 255);"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Right-of-use assets obtained in exchange for new operating lease liabilities</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">144</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">135</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; background-color: rgb(255, 255, 255);"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Weighted-average remaining lease term of operating leases (in years)</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84039588">1.28</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84039589">2.13</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; background-color: rgb(204, 238, 255);"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Weighted-average discount rate of operating leases</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5.78</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">%</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5.36</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">%</td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">As of <em style="font: inherit;"> March 31, 2022, </em>maturities of lease liabilities were as follows (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 90%; margin-left: 5%; margin-right: 5%;"><tbody><tr style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: middle; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: middle; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Operating </b></p> </td></tr> <tr style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Leases</b></p> </td></tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: top; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Years ending December 31,</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: top; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Remainder of 2022</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038925">$ 841</span></p> </td></tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: top; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">2023</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">358</p> </td></tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">2024</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">58</p> </td></tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">2025</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt; text-align: right;">—</p> </td></tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">2026 and thereafter</p> </td><td style="vertical-align: middle; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt; text-align: right;">—</p> </td></tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Total future minimum lease payments</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038930">$ 1,257</span></p> </td></tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 79.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Less: Interest</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">50</p> </td></tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Present value of lease liabilities</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="border-bottom: 3px double rgb(0, 0, 0); vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038932">$ 1,207</span></p> </td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Subleases</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">As of <em style="font: inherit;"> March 31, 2022</em>, undiscounted cash flows to be received under the Company’s operating sublease on an annual basis were as follows (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Operating Leases</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 85%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Years ending December 31,</p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Remainder of 2022</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038934">182</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">2023</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038935">243</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">2024</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038936">251</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">2025</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038937">49</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">2026 and thereafter</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"><span style="-sec-ix-hidden:c84038938">—</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038939">725</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Sublease income is recognized net within operating expense. Sublease income for the <em style="font: inherit;">three</em> months ended <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;">2021</em> was as follows (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Three Months Ended </b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>March 31,</b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>2022</b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>2021</b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 12%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 12%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td></tr> <tr style="vertical-align: bottom; background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Sublease income from fixed lease payments</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">56</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">56</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> </tbody></table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> 200000 600000 500000 P38M 500000 <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Three Months Ended</em></em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">March 31,</em></em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Operating lease cost</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">259</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">267</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Sublease income</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">(56</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">(56</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">)</td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Variable lease cost</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">17</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">22</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">220</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">233</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td></tr> </tbody></table> 259000 267000 56000 56000 17000 22000 220000 233000 <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">March 31,</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">December 31,</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Right of use asset</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">945</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,180</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Long-term lease liabilities</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">277</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">398</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Other current liabilities</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">930</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,089</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> </tbody></table> 945000 1180000 277000 398000 930000 1089000 <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><b>Three Months Ended</b></td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><b>March 31,</b></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><b>2022</b></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><b>2021</b></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; background-color: rgb(204, 238, 255);"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Cash paid for amounts included in the measurement of lease liabilities:</p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; background-color: rgb(255, 255, 255);"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt; margin-left: 9pt;">Operating cash flows from operating leases</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">3,322</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">2,157</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; background-color: rgb(204, 238, 255);"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Right-of-use assets obtained in exchange for new operating lease liabilities</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">144</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">135</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; background-color: rgb(255, 255, 255);"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Weighted-average remaining lease term of operating leases (in years)</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84039588">1.28</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84039589">2.13</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; background-color: rgb(204, 238, 255);"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Weighted-average discount rate of operating leases</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5.78</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">%</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">5.36</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">%</td></tr> </tbody></table> 3322000 2157000 144000 135000 0.0578 0.0536 <table cellpadding="0" cellspacing="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 90%; margin-left: 5%; margin-right: 5%;"><tbody><tr style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: middle; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: middle; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Operating </b></p> </td></tr> <tr style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Leases</b></p> </td></tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: top; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Years ending December 31,</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td></tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: top; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Remainder of 2022</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038925">$ 841</span></p> </td></tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: top; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">2023</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">358</p> </td></tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">2024</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">58</p> </td></tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">2025</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt; text-align: right;">—</p> </td></tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">2026 and thereafter</p> </td><td style="vertical-align: middle; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><em style="font: inherit;"> </em><p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt; text-align: right;">—</p> </td></tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Total future minimum lease payments</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038930">$ 1,257</span></p> </td></tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 79.4%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Less: Interest</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">50</p> </td></tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="vertical-align: bottom; width: 73.3%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Present value of lease liabilities</p> </td><td style="vertical-align: bottom; width: 4.1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="border-bottom: 3px double rgb(0, 0, 0); vertical-align: bottom; width: 22.7%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038932">$ 1,207</span></p> </td></tr> </tbody></table> <table border="0" cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">Operating Leases</em></b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px;"> </td></tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 85%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Years ending December 31,</p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Remainder of 2022</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038934">182</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">2023</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038935">243</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">2024</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038936">251</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">2025</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038937">49</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(255, 255, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">2026 and thereafter</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);"><span style="-sec-ix-hidden:c84038938">—</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td></tr> <tr class="GFJY4-DFU-com-rdg-thunderdome-client-resources-CssResource-html-lineItem-v2v-addition" style="background-color: rgb(204, 238, 255); vertical-align: bottom"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"><span style="-sec-ix-hidden:c84038939">725</span></td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> </tbody></table> 358000 58000 50000 <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"><tbody><tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Three Months Ended </b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>March 31,</b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>2022</b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>2021</b></p> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td></tr> <tr style="vertical-align: bottom; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 12%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 12%;"> </td><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td></tr> <tr style="vertical-align: bottom; background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"><td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Sublease income from fixed lease payments</p> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">56</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td><td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">56</td><td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td></tr> </tbody></table> 56000 56000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">12</em> </b>–<b> Revenue From Product Sales</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Net product sales consist of the following for the <em style="font: inherit;">three</em> months ended <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;">2021</em> (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 12.5%; margin-left: 12.5%; width: 75%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Three Months Ended</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">March 31,</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Jelmyto</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">13,564</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">7,485</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="margin: 0pt; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </p> <p style="margin: 0pt; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </p> <p style="margin: 0pt; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </p> <p style="margin: 0pt; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;">Net revenue recognized includes management’s estimate of returns, consideration paid to the customer, chargebacks relating to differences between the wholesale acquisition cost and the contracted price offered to the end consumer, chargebacks relating to <i><em style="font: inherit;">340b</em></i> drug pricing programs, Medicaid drug rebate programs, and the Company’s copay assistance program, which are estimated based on industry benchmarking studies as well as the Company’s historical experience. Reserves related to items that are contractually able to be net settled are recognized as contra accounts receivables. The following table shows the activity with respect to sales reserves for period ended <em style="font: inherit;"> March 31, 2022 (</em>in thousands):</p> <p style="margin: 0pt; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </p> <table cellpadding="0" cellspacing="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 75%; margin-left: 12.5%; margin-right: 12.5%;"> <tbody> <tr style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: middle; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Reserves related to government sponsored programs</b></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Other reserves</b></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Total accrued sales reserves</b></p> </td> </tr> <tr style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: bottom; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Balance as of December 31, 2021</b></p> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038964">373</span></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038965">1,335</span></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038966">1,708</span></p> </td> </tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: bottom; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Changes during Q1 22</b></p> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: bottom; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Accruals</p> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">873</p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">1,220</p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">2,093</p> </td> </tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: bottom; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Utilizations</p> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038971">(1,001)</span></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038972">(1,411)</span></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038973">(2,412)</span></p> </td> </tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: bottom; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Balance as of March 31, 2022</b></p> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 3px double rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">245</p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 3px double rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">1,144</p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 3px double rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">1,389</p> </td> </tr> </tbody> </table> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 12.5%; margin-left: 12.5%; width: 75%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Three Months Ended</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">March 31,</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Jelmyto</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">13,564</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">7,485</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> </tbody> </table> 13564000 7485000 <table cellpadding="0" cellspacing="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 75%; margin-left: 12.5%; margin-right: 12.5%;"> <tbody> <tr style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: middle; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Reserves related to government sponsored programs</b></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Other reserves</b></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 1px solid rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>Total accrued sales reserves</b></p> </td> </tr> <tr style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: bottom; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Balance as of December 31, 2021</b></p> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038964">373</span></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038965">1,335</span></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038966">1,708</span></p> </td> </tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: bottom; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Changes during Q1 22</b></p> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: bottom; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Accruals</p> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">873</p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">1,220</p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">2,093</p> </td> </tr> <tr style="background-color: rgb(204, 238, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: bottom; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Utilizations</p> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038971">(1,001)</span></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038972">(1,411)</span></p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;"><span style="-sec-ix-hidden:c84038973">(2,412)</span></p> </td> </tr> <tr style="background-color: rgb(255, 255, 255); font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <td style="vertical-align: bottom; width: 25%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Balance as of March 31, 2022</b></p> </td> <td style="vertical-align: middle; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 3px double rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">245</p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 3px double rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">1,144</p> </td> <td style="vertical-align: bottom; width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="border-bottom: 3px double rgb(0, 0, 0); vertical-align: bottom; width: 15%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: right; margin: 0pt;">1,389</p> </td> </tr> </tbody> </table> 873000 1220000 2093000 245000 1144000 1389000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">13</em> </b>–<b> License and Collaboration Agreements</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>Agenus Agreement</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> November 2019, </em>the Company entered into a license agreement with Agenus Inc., pursuant to which Agenus granted to the Company an exclusive, worldwide (<em style="font: inherit;">not</em> including Argentina, Brazil, Chile, Colombia, Peru, Venezuela and their respective territories and possessions), royalty-bearing, sublicensable license under Agenus’s intellectual property rights to develop, make, use, sell, import, and otherwise commercialize products incorporating a proprietary antibody of Agenus known as <em style="font: inherit;">AGEN1884</em> for the treatment of cancers of the urinary tract via intravesical delivery. <em style="font: inherit;">AGEN1884</em> is an anti-CTLA-<em style="font: inherit;">4</em> antagonist that is currently being evaluated by Agenus as a monotherapy in PD-<em style="font: inherit;">1</em> refractory patients and in combination with Agenus’ anti-PD-<em style="font: inherit;">1</em> antibody in solid tumors. Initially, the Company plans to develop <em style="font: inherit;">AGEN1884</em> in combination with UGN-<em style="font: inherit;">201</em> for the treatment of high-grade NMIBC.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Pursuant to the license agreement, the Company paid Agenus an upfront fee of $10.0 million and has agreed to pay Agenus up to $115.0 million upon achieving certain clinical development and regulatory milestones, up to $85.0 million upon achieving certain commercial milestones, and royalties on net sales of licensed products in the 14%-20% range. The Company will be responsible for all development and commercialization activities. Under the terms of the license agreement, Agenus has agreed to use commercially reasonable efforts to supply <em style="font: inherit;">AGEN1884</em> to the Company for use in preclinical studies or clinical trials.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Unless earlier terminated in accordance with the terms of the license agreement, the license agreement will expire on a product-by-product and country-by-country basis at the later of (a) the expiration of the last to expire valid claim of a licensed patent right that covers the licensed product in such country or (b) 15 years after the <em style="font: inherit;">first</em> commercial sale of the licensed product in such country. The Company <em style="font: inherit;"> may </em>terminate the license agreement for convenience upon <em style="font: inherit;">180</em> days’ written notice to Agenus. Either party <em style="font: inherit;"> may </em>terminate the license agreement upon <em style="font: inherit;">60</em> days’ notice to the other party if, prior to the <em style="font: inherit;">first</em> commercial sale of a licensed product, the Company substantially ceases to conduct development activities of the licensed products for <em style="font: inherit;">nine</em> consecutive months (and during such period, Agenus has complied with its obligations under the license agreement) other than in response to a requirement of an applicable regulatory authority or an event outside of the Company’s control. In addition, either party <em style="font: inherit;"> may </em>terminate the license agreement in the event of an uncured material breach of the other party.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b><i>MD Anderson Agreement</i></b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> January 2021, </em>the Company announced that it entered into a <span style="-sec-ix-hidden:c84038998">three</span>-year strategic research collaboration agreement with MD Anderson focusing on the sequential use of UGN-<em style="font: inherit;">201</em> and UGN-<em style="font: inherit;">301</em> as an investigational treatment for high-grade NMIBC. Under the agreement, MD Anderson and the Company will collaborate on the design and conduct of non-clinical and clinical studies with oversight from a joint steering committee. The Company will provide funding, developmental candidates, and other support. Pursuant to the agreement, the Company makes bi-annual payments to MD Anderson to fund the collaboration. As of <em style="font: inherit;"> March 31, 2022</em>, the Company has made payments to MD Anderson of $1,000,000 recognized evenly over the associated period through research and development expense.</p> 10000000.0 115000000.0 85000000.0 0.14 0.20 P15Y 1000000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">14</em> </b>–<b> Shareholders</b>’<b> Equity </b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company had 100.0 million ordinary shares authorized for issuance as of <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;"> December 31, 2021</em>. The Company had 22.7 million and 22.5 million ordinary shares issued and outstanding as of <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;"> December </em><em style="font: inherit;">31,</em> <em style="font: inherit;">2021,</em> respectively. Each ordinary share is entitled to <em style="font: inherit;">one</em> vote. The holders of ordinary shares are also entitled to receive dividends whenever funds are legally available, when and if declared by the Board of Directors (the “Board”). Since its inception, the Board has <em style="font: inherit;">not</em> declared any dividends.</p> 100000000.0 22700000 22500000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">15</em> </b>–<b> Share-Based Compensation</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> October 2010, </em>the Board approved a share option plan (the “Plan”) for grants to Company employees, consultants, directors, and other service providers.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The grant of options to Israeli employees under the Plan is subject to the terms stipulated by Section <em style="font: inherit;">102</em> of the Israeli Income Tax Ordinance (“Section <em style="font: inherit;">102”</em>). The option grants are subject to the track chosen by the Company, either the “regular income” track or the “capital gains” track, as set out in Section <em style="font: inherit;">102.</em> The Company registered the Plan under the capital gains track, which offers more favorable tax rates to the employees. As a result, and pursuant to the terms of Section <em style="font: inherit;">102,</em> the Company is <em style="font: inherit;">not</em> allowed to claim as an expense for tax purposes the amounts credited to the employees in respect of options granted to them under the Plan, including amounts recorded as salary benefits in the Company’s accounts, with the exception of the work-income benefit component, if any, determined on grant date. For non-employees and for non-Israeli employees, the Plan is subject to Section <em style="font: inherit;">3</em>(i) of the Israeli Income Tax Ordinance.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">Employees are typically granted stock options and/or restricted stock units ("RSUs"), upon commencement of employment. Also, eligible employees <em style="font: inherit;"> may </em>receive an annual grant of options or RSUs. Non-employee members of the Board typically receive a grant of stock options and/or RSUs annually. The term of any option granted under the Plan cannot exceed 10 years. Options shall <em style="font: inherit;">not</em> have an exercise price less than 100% of the fair market value of the Company’s ordinary shares on the grant date, and generally vest over a period of <span style="-sec-ix-hidden:c84039026">three</span> years. If the individual possesses more than 10% of the combined voting power of all classes of equity of the Company, the exercise price shall <em style="font: inherit;">not</em> be less than 110% of the fair market value of an ordinary share on the date of grant.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company’s RSU and option grants provide for accelerated or continued vesting in certain circumstances as defined in the plans and related grant agreements, including a termination in connection with a change in control. RSUs generally vest in a 33% increment upon the <em style="font: inherit;">first</em> anniversary of grant, and in either equal quarterly or annual amounts for the <span style="-sec-ix-hidden:c84039032">two</span> years following the <em style="font: inherit;">one</em>-year anniversary of the grant date. Options generally vest in a 33% increment upon the <em style="font: inherit;">first</em> anniversary of the grant date, and in either equal quarterly or annual amounts for the <span style="-sec-ix-hidden:c84039036">two</span> years following the <em style="font: inherit;">one</em>-year anniversary of the grant date.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The expected volatility is based on a mix of the Company’s historical volatility, and the historical volatility of comparable companies with similar attributes to the Company, including industry, stage of life cycle, size and financial leverage. The risk-free interest rate assumption is based on observed interest rates appropriate for the expected term of the options granted. The expected term is the length of time until the expected dates of exercising the options and is estimated for employees using the simplified method due to insufficient specific historical information of employees’ exercise behavior, and for non-employees, and directors using the contractual term.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> March 2017, </em>the Board adopted the <em style="font: inherit;">2017</em> Equity Incentive Plan (the <em style="font: inherit;">"2017</em> Plan"), which was approved by the shareholders in <em style="font: inherit;"> April 2017. </em>The <em style="font: inherit;">2017</em> Plan provides for the grant of stock options, stock appreciation rights, restricted stock awards, RSU awards, performance share awards, performance cash awards, and other forms of share awards to the Company's employees, directors and consultants.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The maximum number of ordinary shares that was initially authorized for issuance under the <em style="font: inherit;">2017</em> Plan is 1,400,000. On <em style="font: inherit;"> January 1, 2018, </em>the share reserve increased by 250,167 to 1,650,167. On <em style="font: inherit;"> October 12, 2018, </em>the Company increased the amount of registered ordinary shares of the Company’s <em style="font: inherit;">2017</em> Plan by 1,900,000 to 3,550,167. On <em style="font: inherit;"> June 8, 2020 </em>the Company’s shareholders approved an increase to the amount of registered ordinary shares of the Company’s <em style="font: inherit;">2017</em> Plan by 400,000 to 3,950,167. On <em style="font: inherit;"> June 7, 2021, </em>the Company’s shareholders approved an increase of the amount of registered ordinary shares of the Company’s <em style="font: inherit;">2017</em> Plan by 400,000 to 4,350,167.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In <em style="font: inherit;"> May 2019, </em>the Company adopted the UroGen Pharma Ltd. <em style="font: inherit;">2019</em> Inducement Plan (the “Inducement Plan”). Under the Inducement Plan, the Company is authorized to issue up to 900,000 ordinary shares pursuant to awards issued under the Inducement Plan. The only persons eligible to receive grants of Awards (as defined below) under the Inducement Plan are individuals who satisfy the standards for inducement grants under Nasdaq Marketplace Rule <em style="font: inherit;">5635</em>(c)(<em style="font: inherit;">4</em>) or <em style="font: inherit;">5635</em>(c)(<em style="font: inherit;">3</em>) and the related guidance under Nasdaq IM <em style="font: inherit;">5635</em>-<em style="font: inherit;">1,</em> including individuals who were <em style="font: inherit;">not</em> previously an employee or director of the Company or are following a bona fide period of non-employment, in each case as an inducement material to such individual’s agreement to enter into employment with the Company. Under the Inducement Plan, an “Award” is a nonstatutory stock option, RSU or other right to receive ordinary shares pursuant to the Inducement Plan. In <em style="font: inherit;"> December 2021, </em>the Board approved a 300,000 increase in the share reserve of the Inducement Plan.       </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><span style="background-color:#ffffff;">As of </span><em style="font: inherit;"> March 31, 2022</em><span style="background-color:#ffffff;">, 3,949,544 ordinary shares are subject to outstanding awards under the Company's share-based compensation plans and 722,810 ordinary shares remain available for future awards.</span></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The following table illustrates the effect of share-based compensation on the condensed consolidated statements of operations (in thousands):</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Three Months Ended</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">March 31,</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Research and development expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">726</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,107</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Selling, general and administrative expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,223</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">5,088</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">2,949</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">6,195</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The total unrecognized compensation cost of options and RSUs at <em style="font: inherit;"> March 31, 2022</em> is $17.5 million with a weighted average recognition period of 1.96 years.</p> P10Y 1 0.10 1.10 0.33 0.33 1400000 250167 1650167 1900000 3550167 400000 3950167 400000 4350167 900000 300000 3949544 722810 <table cellpadding="0" cellspacing="0" class="finTable" style="margin-right: 5%; margin-left: 5%; width: 90%; font-size: 10pt; font-family: Arial, Helvetica, sans-serif; text-indent: 0px;"> <tbody> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">Three Months Ended</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="6" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 16%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;"><em style="font: inherit;">March 31,</em></em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2022</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 1%;"> </td> <td colspan="2" style="text-align: center; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0); width: 1%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b><em style="font: inherit;">2021</em></b></p> </td> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; width: 1%;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Research and development expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">726</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;">1,107</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(255, 255, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin-top: 0pt; margin-bottom: 0pt;">Selling, general and administrative expense</p> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">2,223</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 1px solid rgb(0, 0, 0);">5,088</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 1px; margin-left: 0pt;"> </td> </tr> <tr style="background-color: rgb(204, 238, 255); vertical-align: bottom"> <td style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 70%;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">2,949</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt;"> </td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">$</td> <td style="width: 12%; text-align: right; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; margin-left: 0pt; border-bottom: 3px double rgb(0, 0, 0);">6,195</td> <td style="width: 1%; font-family: Arial, Helvetica, sans-serif; font-size: 10pt; padding-bottom: 3px; margin-left: 0pt;"> </td> </tr> </tbody> </table> 726000 1107000 2223000 5088000 2949000 6195000 17500000 P1Y11M15D <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">16</em> </b>–<b> Income Taxes </b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">UroGen Pharma Ltd. is taxed under Israeli tax laws. As of <em style="font: inherit;"> March 31, 2022</em>, the Company continues to maintain a full valuation allowance against deferred tax assets for all jurisdictions. In evaluating the need for a valuation allowance, the Company considers all sources of taxable income available to realize the deferred tax asset, including the future reversal of existing temporary differences, forecasts of future taxable income, and tax planning strategies. The Company has cumulative global pretax losses for the years ended <em style="font: inherit;">2021,</em> <em style="font: inherit;">2020</em> and <em style="font: inherit;">2019,</em> and for the <em style="font: inherit;">three</em> months ended <em style="font: inherit;"> March 31, 2022</em>. The Company will continue to assess the extent to which its deferred tax assets <em style="font: inherit;"> may </em>be realized in the future and will adjust the valuation allowance as needed.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company has a liability for uncertain tax positions of $2.8 million as of <em style="font: inherit;"> March 31, 2022</em>, for tax positions relating to transfer pricing between affiliated entities. The Company recognizes interest accrued and penalties related to uncertain tax positions as a component of income tax expense. As of <em style="font: inherit;"> March 31, 2022</em>, the Company’s liability for uncertain tax positions includes $0.9 million of accrued interest and penalties.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company operates on a global basis and is subject to tax laws and regulations in the U.S. and Israel. The estimate of the Company’s tax liabilities relating to uncertain tax positions requires management to assess uncertainties and to make judgments about the application of complex tax laws and regulations, expectations regarding the outcome of tax authority examinations, as well as the ultimate measurement of potential liabilities.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The uncertain tax positions are reviewed quarterly and adjusted as events occur that could affect potential liabilities for additional taxes, including lapsing of applicable statutes of limitations, correspondence with tax authorities, proposed assessments by tax authorities, identification of new issues, and issuance of new legislation or regulations. The Company believes that adequate amounts of tax have been provided in income tax expense for any adjustments that <em style="font: inherit;"> may </em>result from its uncertain tax positions. Based upon the information currently available, the Company does <em style="font: inherit;">not</em> reasonably expect changes in its existing uncertain tax positions in the next <em style="font: inherit;">12</em> months and has recorded the gross uncertain tax positions as a long-term liability.</p> 2800000 900000 <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">17</em> </b>–<b> Related Parties</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">There were <em style="font: inherit;">no</em> related party transactions for the <em style="font: inherit;">three</em> months ended <em style="font: inherit;"> March 31, 2022</em> or <em style="font: inherit;">2021</em>.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">18</em> </b>–<b> Commitments and Contingencies </b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">In the normal course of business, the Company enters into contracts that contain a variety of indemnifications with its employees, licensors, suppliers and service providers. Further, the Company indemnifies its directors and officers who are, or were, serving at the Company’s request in such capacities. The Company’s maximum exposure under these arrangements is unknown as of <em style="font: inherit;"> March 31, 2022</em> and <em style="font: inherit;"> December 31, 2021</em>. The Company does <em style="font: inherit;">not</em> anticipate recognizing any significant losses relating to these arrangements.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><i>Leases</i></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">See Note <em style="font: inherit;">11</em> for further discussion regarding lease commitments.</p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"><b>Note <em style="font: inherit;">19</em> </b>–<b> Subsequent Events</b></p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;"> </p> <p style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; font-variant: normal; margin: 0pt;">The Company has evaluated and determined there were <em style="font: inherit;">no</em> subsequent events through <em style="font: inherit;"> May 10, 2022.</em></p> $1.0 million of raw materials at December 31, 2021 are included within other non-current assets on the condensed consolidated balance sheets. $1.5M of the Amounts paid and payable are included as current portion of the prepaid forward obligation within other current liabilities on the balance sheet